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BIMSA Computational Math Seminar
Efficient blood flow simulations with a multiscale mathematical model for the cardiovascular system
Efficient blood flow simulations with a multiscale mathematical model for the cardiovascular system
Organizers
Speaker
Jiawei Liu
Time
Monday, November 11, 2024 3:00 PM - 4:00 PM
Venue
Online
Online
Zoom 928 682 9093
(BIMSA)
Abstract
The presented multi-scale, closed-loop blood circulation model includes arterial, venous, and portal venous systems, heart-pulmonary circulation, and micro-circulation in capillaries. One-dimensional models simulate large blood vessel flow, whereas zero-dimensional models are used for simulating blood flow in vascular subsystems corresponding to peripheral arteries and organs. Transmission conditions at bifurcation and confluence are solved using Riemann invariants. Blood circulation simulation in the portal venous system and related organs (liver, stomach, spleen, pancreas, intestine) is particularly targeted. Those organs play important roles in metabolic system dynamics. In addition, proposed efficient parallel algorithms for multicore environments solve these equations much faster than serial computations.
Speaker Intro
Dr. Jiawei Liu is currently an Assistant Professor at the Advanced Institute for Materials Research (WPI-AIMR), Tohoku University, Japan. She received her Ph.D. degree from Tsinghua University and previously worked as a Postdoctoral Research Fellow at the School of Geophysics and Information Physics, Central South University, China.
Her research interests include multiscale modeling of the human circulatory system, coupled regulation of cerebral and cardiovascular hemodynamics, and parallel numerical simulation of physiological systems. She has developed an interactive visualization and simulation app integrating whole-body circulation, cerebral blood flow, and heart–lung dynamics, which is now being jointly studied with medical teams from The University of Tokyo and Tohoku University. Dr. Liu has published more than ten papers as the first or corresponding author in international journals such as Geophysical Journal International and Geophysical Prospecting, led one provincial-level Natural Science Foundation project, and holds three national invention patents. Her current research focuses on establishing a unified theoretical and computational framework for understanding and predicting blood circulatory regulation of the whole body and disease progression through multiscale modeling and computational physiology.