Single-cell RNA-sequencing (scRNA-seq) data integration
Organizer
Speaker
(Tsinghua) Tao Zhou
Time
Thursday, February 15, 2024 9:00 PM - 9:30 PM
Venue
Online
Abstract
It is inevitable that scRNA-seq data are generated in multiple laboratories using different cell dissociation and handling protocols, library-preparation technologies and sequencing platforms. All these factors will result in batch effects which means the expression of genes in one batch differs systematically from that in another batch. In order to unravel the underlying biological structure beside the data and to avoid misleading conclusions, one must correct the data before analysis, which triggered the topic of scRNA-seq data integration. This week we will present the development of scRNA-seq data integration methods, as well as suggest some possible ideas for data integration.