Fundamental Population and Quantitative Genetics on Evolution
With The mathematical theory of the evolution of complex traits as the clue, the final concern is the synthesis of palaeobiology theory and genetics theory, and the core contents of population genetics and quantitative genetics are connected around the evolutionary theory. Emphasis is placed on the introduction and lecture of mathematical content in population and quantitative genetics. This course is the lead course of Natural Selection and Evolution of Quantitative Traits.
以复杂性状的演化的数学理论为线索，以进化论中古生物学理论和遗传学理论的大综合为最终关切（我相信这是未来进化生物学的某种方向和趋势），围绕进化理论串联种群遗传学和数量遗传学核心内容。尤其注重对种群和数量遗传学中数学内容的介绍和串讲。本课程是数量性状的自然选择与演化课程的先导课程。
以复杂性状的演化的数学理论为线索，以进化论中古生物学理论和遗传学理论的大综合为最终关切（我相信这是未来进化生物学的某种方向和趋势），围绕进化理论串联种群遗传学和数量遗传学核心内容。尤其注重对种群和数量遗传学中数学内容的介绍和串讲。本课程是数量性状的自然选择与演化课程的先导课程。
Lecturer
Date
29th September, 2025 ~ 29th January, 2026
Location
| Weekday | Time | Venue | Online | ID | Password |
|---|---|---|---|---|---|
| Monday | 14:20 - 16:55 | A3-2-301 | Tencent 62 | 839 079 0573 | 271828 |
Syllabus
overview of modern life sciences
major goals of quantitative genetics and properties of distribution
covariance, regression, and correlation of quantitative trait
Properties of single locus
Sources of genetic variation for multilocus traits + Components of environmental variation
Resemblance between relatives
Polygenes and polygenic mutation
Parent-offspring regression
neutral evolution in one and two-locus systems (1)
neutral evolution in one and two-locus systems (2)
the genetic effective population size
the nonadaptive forces of evolution
population genetics of selection (1)
population genetics of selection (2)
interaction of selection, mutation and drift (1)
interaction of selection, mutation and drift (2)
major goals of quantitative genetics and properties of distribution
covariance, regression, and correlation of quantitative trait
Properties of single locus
Sources of genetic variation for multilocus traits + Components of environmental variation
Resemblance between relatives
Polygenes and polygenic mutation
Parent-offspring regression
neutral evolution in one and two-locus systems (1)
neutral evolution in one and two-locus systems (2)
the genetic effective population size
the nonadaptive forces of evolution
population genetics of selection (1)
population genetics of selection (2)
interaction of selection, mutation and drift (1)
interaction of selection, mutation and drift (2)
Reference
教材：
Michael Lynch & Bruce Walsh. Genetics and Analysis of QUantitative Traits. Oxford University Press. 1998.
Bruce Walsh & Michael Lynch. Evolution and Selection of Quantitative Traits. Oxford University Press. 2018.
参考书：
刘祖洞、吴燕华、乔守怡、赵寿元。遗传学（第4版），高等教育出版社，2021-3.
Daniel Hartl，Andrew Clark. Principles of Population Genetics, Fourth Edition, Sinauer Associates, Inc. 2007.
Warren J. Ewens. Mathematical Population Genetics. Springer. 2004-1
Michael Lynch & Bruce Walsh. Genetics and Analysis of QUantitative Traits. Oxford University Press. 1998.
Bruce Walsh & Michael Lynch. Evolution and Selection of Quantitative Traits. Oxford University Press. 2018.
参考书：
刘祖洞、吴燕华、乔守怡、赵寿元。遗传学（第4版），高等教育出版社，2021-3.
Daniel Hartl，Andrew Clark. Principles of Population Genetics, Fourth Edition, Sinauer Associates, Inc. 2007.
Warren J. Ewens. Mathematical Population Genetics. Springer. 2004-1
Audience
Advanced Undergraduate
, Graduate
Video Public
Yes
Notes Public
Yes
Language
Chinese
, English