Biography

Research Interest

• evolutionary dynamics of complex trait
• alignment-free methods for sequence analysis

Education Experience

• 2000 - 2006 | Fudan University | Genetics | Doctor | Joint Master's and Doctoral Program | (Supervisor: Long Yu)
• 1996 - 2000 | Hebei University | Microbiology | B.Sc. | (Supervisor: Liping Zhang)

Work Experience

• -- - -- | Institute of Biomedical Sciences, Fudan University | Postdoctoral Fellow
• -- - -- | State Key Laboratory of Genetic Engineering, Fudan University | Research Assistant
• -- - -- | Institute of Zoology, Chinese Academy of Sciences | Assistant Researcher and Associate Researcher
• -- - -- | Institute of Microbiology, Chinese Academy of Sciences | PI, Associated professor | Doctoral supervisor
• -- - 2026 | Beijing Institute of Mathematical Sciences and Applications (BIMSA) | Associated professor

Honors and Awards

• 2019 | Second Prize of the National Natural Science Award | "Adaptive Evolution and Endangerment Mechanisms of Giant Pandas", Fourth Contributor

Publications

• [1] Qi Wu, Xiuting Gu, Yu Wang, Nan Li, Xianghua Liu, Chaoqun Wu, Long Yu* and Xun Gu*, Neurotransmitter inactivation is important for the origin of nerve system in animal early evolution: A suggestion from genomic comparison, Progress in Neurobiology, 78(2006), 6, 390-395
• [2] Lifeng Zhu#, Qi Wu#, Jiayin Dai, Shanning Zhang, Fuwen Wei*, Evidence of cellulose metabolism by the giant panda gut microbiome, PNAS, 108(43), 17714-17719 (2011)
• [3] Shancen Zhao#, Pingping Zheng#, Shanshan Dong#, Xiangjiang Zhan#, Qi Wu#, ... Jun Wang* & Fuwen Wei*, Whole-genome sequencing of giant pandas provides insights into demographic history and local adaptation, Nature Genetics, 45(2013), 1, 67-U99
• [4] Yonggang Nie#, John R. Speakman#, Qi Wu#, Chenglin Zhang, Yibo Hu, Maohua Xia, Li Yan, Catherine Hambly, Lu Wang, Wei Wei, Jingguo Zhang, Fuwen Wei*, Exceptionally low daily energy expenditure in the bamboo-eating giant panda, Science, 349(2015), 6244, 171-174
• [5] Yibo Hu#, Qi Wu#, Shuai Ma#, Tianxiao Ma#, Lei Shan, Xiao Wang, Yonggang Nie, Zemin Ning, Li Yan, Yunfang Xiu, Fuwen Wei*, Comparative genomics reveals convergent evolution between the bamboo-eating giant and red pandas, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114(2016), 5, 1081-1086
• [6] Qi Wu, Yadi Wang, Yun Ding, Shuai Ma, Zongmin Wu*, Fuwen Wei*, A natural communication system on genome evolution, Science China - Life Science, 60(2017), 4, 432-435
• [7] Shuai Liu#, Shaojun Pei#, Stephen S.-T. Yau*, and Qi Wu*, Assessment of kmer degeneration method for complicated genomes., Communications in Information and Systems, 19(2019), 1, 17-35
• [8] Huizhong Fan#, Qi Wu#, Fuwen Wei, Fengtang Yang, Bee Ling Ng & Yibo Hu*, Chromosome-level genome assembly for giant panda provides novel insights into Carnivora chromosome evolution., Genome Biology, 20(2019), 1, 267
• [9] Jiuhong Dong#, Shuai Liu#, Yaran Zhang, Yi Dai and Qi Wu*, A New Alignment-Free Whole Metagenome Comparison Tool and Its Application on Gut Microbiomes of Wild Giant Pandas., Frontiers in Microbiology, 11(2020), 1061
• [10] Huizhong Fan, Lei Chen, Yibo Hu, Guohui Shi, Yi Dai, Fuwen Wei, and Qi Wu, A whole-genome association approach for large-scale interspecies traits, SCIENCE CHINA Life Sciences, 64(2021), 1372-1374
• [11] Zhilin Yuan#, Qi Wu#, Liangxiong Xu#, Irina S Druzhinina#, ... Francis M Martin*, Genomic landscape of a relict fir-associated fungus reveals rapid convergent adaptation towards endophytism, ISME J, 16(2022), 5, 1294-1305
• [12] Yi Dai, Guohui Shi, Mengmeng Chen, Guotao Chen, Qi Wu*, Using Polygenic Risk Scores Related to Complex Traits to Predict Production Performance in Cross-Breeding of Yeast, Journal of Fungi, 8(2022), 9, 914
• [13] Meng-Meng Chen, Guo-Hui Shi, Yi Dai, Wen-Xia Fang, Qi Wu*, Identifying genetic variants associated with amphotericin B (AMB) resistance in Aspergillus fumigatus via k- mer - based GWAS, Frontiers in Genetics, 14(2023), 1133593
• [14] Guohui Shi, Yi Dai , Da Zhou , Mengmeng Chen , Jiaqi Zhang , Yilong Bi , Shuai Liu & Qi Wu*, An alignment- and reference-free strategy using k-mer present pattern for population genomic analyses, Mycology(2024)
• [15] Mengcen Guan, Qi Wu, Xin Zhao, and Stephen S.-T. Yau, Using Natural Vector Method for Population Genomic 1 Analysis on Human Mitochondrial Genome Data, biorxiv (2025)
• [16] Qi Wu, Jingyan Li, Guoqing Hu, Piyu Zhou, Xin Zhao, Stephen S.-T. Yau, Primitive GLMY Homology: An Algebraic Topology Approach for the Quantitative Characterization of Graph Pangenomes toward Population Genetic Analysis, biorxiv (2026)
• [17] 石想, 康家熠, 赵鑫, 孙楠, 丘成栋, 吴琦, 多基因性状表型加性方差在进化中的维持 (2026)
• [18] Xiang Shi, Jiayi Kang, Xin Zhao , Nan Sun, Stephen S.-T. Yau, Qi Wu, Prolonged maintenance of polygenic polymorphism under stabilizing selection alone (2026)