北京雁栖湖应用数学研究院 北京雁栖湖应用数学研究院

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关于我们
院长致辞
理事会
协作机构
参观来访
人员
管理层
科研人员
博士后
来访学者
行政团队
学术研究
研究团队
公开课
讨论班
招生招聘
教研人员
博士后
学生
会议
学术会议
工作坊
论坛
学院生活
住宿
交通
配套设施
周边旅游
新闻
新闻动态
通知公告
资料下载
清华大学 "求真书院"
清华大学丘成桐数学科学中心
清华三亚国际数学论坛
上海数学与交叉学科研究院
BIMSA > Game Theory Seminar idopNetwork as a tool to dissect complex systems
idopNetwork as a tool to dissect complex systems
组织者
邬荣领 , 张蓥莹
演讲者
董昂
时间
2023年11月08日 14:00 至 15:45
地点
Shuangqing-B725
摘要
The past few years have seen the development of powerful computational models for reconstructing informative, dynamic, omnidirectional, and personalized networks (idopNetworks) of complex systems. We pack an R-based cartographic tool for idopNetwork reconstruction from any data. The tool includes several key steps, including fitting power curve fitting based on allometrical scaling law, functional clustering, LASSO-based variable selection, quasi-dynamic ordinary differential equation solving, species abundance decomposition and network visualization. Ultimately, it can coalesce all nodes into multilayer idopNetworks. We demonstrate the utility of this tool by analyzing different organs that are spatially interconnected via microbiomes using two datasets from the gut microbiota and plant microbiota. Given that biodiversity and organization vary biogeographically at different scales, idopNetwork will find its widespread application to modelling and estimating interspecific interactions with differing functions across space.
演讲者介绍
Dr.Dong received his education in Biotechnology and Silviculture at Zhejiang A&F University in 2018, then earned his Ph.D. at Beijing Forestry University in 2023. He is broadly interested in the role that network theory plays in paradigm shift in the life sciences, his current research lies at the area of statistical modelling and computer programming. He is working on how to fully utilize existing data to build a network which can analysis the detailed regulatory relationship between genes during the complicated biological process and how to make this idea come true. He also uses computer simulation that allows exploration and verification of design model parameters in multiple scenarios, and helps to further improve and understand the model as well as the complex systems.
北京雁栖湖应用数学研究院
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